By tracking the changes in prostate cancer cells over time, researchers at the Johns Hopkins Kimmel Cancer Center have found that activation of the MYC gene -; a well-known cancer-causing gene -; sets ...

For more information, please refer to the full article in JAMA Oncology.

Areas of emphasis include cell cycle and senescence; cell death and survival; chromatin, gene and RNA regulation; DNA damage and repair; genomics; oncogenes and tumor suppressors; and signal ...

By tracking the changes in prostate cancer cells over time, researchers at the Johns Hopkins Kimmel Cancer Center have found ...

@hopkinskimmel investigators find that activation of the MYC gene induces a cascade of events leading to #prostatecancer ...

In these mice, part of the Trp53 gene had been mutated to remove the cell’s ability to make isoforms with an alternative C-terminal end. Fajac et al. then allowed these mice to breed with mice that ...

Proto-oncogenes regulate cell growth; mutations convert them to oncogenes, leading to cancer by disrupting normal cell division processes.

Treatment with OTX-2002 led to controlled downregulation of MYC gene expression and resulted in significant inhibition of tumor growth as a ...

The University of Cincinnati Cancer Center's Eric Vick, MD, PhD, has been awarded a nearly $215,000 Career Development Award from the Leukemia and Lymphoma Society (LLS) and a $50,000 American Society ...

Activated coiled-coil (CC) domain containing NLRs (CNLs) oligomerize and form apparent cation channels promoting calcium influx and cell death, with the alpha-1 helix of the individual CC domains ...

The University of Cincinnati Cancer Center’s Eric Vick, MD, PhD, has been awarded a nearly $215,000 grant from the Leukemia ...

The humble T-shirt has become wardrobe royalty. Every stylish person, from office executives to skaters to travelers, has spent time — or is currently — hunting for that perfect tee they can ...