Enter the game-changer—two Pt-MSA-2 conjugates (I and II). These ingenious compounds bring together the DNA-damaging power of cisplatin and the immune-activating strength of STING agonist MSA-2.

But these enzymes are also known to mutate other cells' DNA sometimes. This research has determined that chemotherapy can be ...

Another drug that’s in short supply is cisplatin, which has been the backbone for lung cancer regimens for many years. The National Comprehensive Cancer Network, an alliance of 33 U.S. cancer ...

Combination therapy with enfortumab vedotin (Padcev) and pembrolizumab (Keytruda) was associated with durable responses and ...

Cisplatin is one of the most widely used agents in the treatment of solid tumors, but its clinical utility is limited by toxicity. The development of less toxic, liposomal formulations of ...

Q3 2024 Earnings Call Transcript November 9, 2024 Operator: Good morning, ladies and gentlemen, and welcome to Fennec ...

Transferred US sponsorship of global Phase 3 NANORAY-312 head and neck cancer study, a key step in the preparation for potential NBTXR3 ...

The global burden of digestive tract tumors is profound, with these cancers accounting for nearly half of all malignant ...

Ferroptosis offers new strategies to combat treatment resistance in digestive tract cancers, enhancing the efficacy of ...

Perioperative durvalumab has “the potential to transform the standard of care” for patients with muscle-invasive bladder ...

Fully enrolled the Phase 2/3 trial of lead asset CTX-009 (DLL4 and VEGF-A bispecific antibody) in patients with biliary tract cancers (BTC); ...

Capsaicin, the compound in chili peppers which gives them their spicy taste, may become a source of new, natural drugs for ...